Tender Summary

Process and Impact Evaluation

Buying Organisation

Genomics England

Contract Value

Unknown

Tender Description

Genomics Englands Generation Study aims to explore the benefits, challenges, and practicalities of offering whole genome sequencing to newborns, to accelerate diagnosis and access to treatment for rare genetic conditions. The programme funding was confirmed on 13 December 2022 with 105 million of funding to support it. Should it prove beneficial for participants and the wider health service, the study could pave the way for what would be the worlds first national newborn screening programme to incorporate whole genome sequencing.
The outcome for this project is for Genomics England to work in partnership with an organisation or group of organisations with the specific expertise to deliver the Generation Study evaluation. The Generation Study will:
1. evaluate the scientific and clinical utility and validity, operational feasibility, and impact on the NHS of using Whole Genome Sequencing to screen for a large number of childhood-onset rare genetic conditions and provide ongoing patient support
2. understand how, with consent, newborns genomic and health data could be used for research to enable new diagnostic discoveries and treatments to be developed
3. explore the potential risks, benefits, and broader implications of storing an individuals genome over their lifetime (e.g., potential for preventative steps, personalised risk-based screening in later life etc.)
Please note that this tender seeks a partner to evaluate the first of these three aims only.

Tender categories (products & services required)

Research consultancy services (CPV 73210000)
Research and development services and related consultancy services (CPV 73000000)

Region

London (UKI)

Buyer Information